therapeutic possibilities, including rare diseases or extremely expensive, complex and long-term treatments; • Research to continually improve care and develop new treatments; • Training of doctors, midwives

Investor Strategies for Incorporating ESG Considerations into Corporate Interactions www.blackrock.com www.ceres.org Century21st Engagement Investor Strategies for Incorporating ESG Considerations into Corporate Interactions [ 5 ] FOREWORD The Value of Our Voice ......................................................................................................................................... 1 How ESG Megatrends Are Shaping Valuation ...........................................................